TB-500 (Thymosin Beta-4 Fragment)
TB-500 is a synthetic peptide derived from the naturally occurring protein thymosin beta-4, a 43-amino acid peptide present in nearly all human and animal cells. At Dobry Peptides, TB-500 is supplied exclusively for laboratory research and in-vitro scientific investigation.
This peptide is widely utilized in experimental models examining cellular migration, angiogenesis, and tissue repair signaling. Its ability to promote actin regulation at the cellular level has made it one of the most frequently studied peptides in regenerative research.
Overview
TB-500 upregulates the expression of actin, a cell-building protein critical for cellular structure, movement, and repair. In preclinical models, TB-500 has been observed to promote endothelial cell migration and differentiation, support new blood vessel formation, and modulate inflammatory cytokine activity.
Its mechanism of action centers on interaction with actin-binding sites, facilitating cellular motility and enabling cells to migrate toward sites of injury or inflammation. This has made TB-500 a subject of significant interest in studies examining wound repair, vascular function, and connective tissue biology.
- Widely studied in tissue repair and cellular migration research
- Promotes actin regulation and endothelial cell differentiation
- Investigated for angiogenesis and vascular remodeling pathways
- Modulates inflammatory response in preclinical models
- Derived from naturally occurring thymosin beta-4 protein
- Non-anabolic and non-steroidal research peptide
- Suitable for in-vitro and preclinical laboratory investigations
Specifications
- Peptide Type: Actin-regulating peptide (thymosin beta-4 fragment)
- Molecular Weight: ~4,963 g/mol
- Appearance: White lyophilized powder
- Storage: Store at -20°C, protect from light
- For research use only. Not for human consumption.





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